General DAC column specification

Specifications include:
Column diameter 50mm - 1,600mm
Packed bed length 50mm - 1,500mm
Design pressure 2bar - 100bar
Design flow according to customer requirement
High performance packing
Special designed distributor design ensures even flow across the bed
Slurry inlet valve for quick and easy packing
Slurry outlet valve for quick and easy unpacking, without opening the column
Repacking without opening the column
Reproducible packing each time
The packing can be automated

Column sanitary design

Inlet and outlet valve in sanitary design, connections are sanitary design with minimized dead volumes inside columns allowing complete CIP flexibility.

Mobile construction makes it possible to move the columns around within the facility, e.g. when necessary to do column packing in one area and production in another area. There is easy installation and connection to other equipment.

They feature removable frit plates for easy replacement, in order to cleaning purpose or product change. Frit plates are available within a range of frit pore sizes from 2µ to 75µm.
Column materials and construction
All columns are CE-marked and cGMP compliant
Parts in product contact: Stainless Steel 316L, duplex or hastelloy
PEHD or PTFE sealings in FDA approved materials (USP Class VI is optional)
Construction codes: PED for Europe
ASME for US
Design codes: ASME BP
Chromatography systems

Low, medium and high pressure chromatography systems

Peak Biotech LC systems are available for low, medium and high pressure chromatography applications, in pilot to production scale.

The systems are designed for continues or batch processing and in compliance with all relevant standards within the pharmaceutical and biotech industry. The systems are custom designed to fit the customer requirements with many different configurations and options.

Systems are available in linear gradient, step gradient or isocratic version. High focus on safety and ergonomic design.

General system specification include:
Flow rate from 6 l/h - 5,000 l/h
Design pressure 2bar - 100bar
Gradient performance
High accuracy gradient mixing loop with feedback from conductivity, NIR or other inline instrument
Inline mixing from 0% - 100% with accuracy below 1% of FS (full scale)
Inline degassing gradient loop
Systems are available in gradients or isocratic versions

Materials and construction code

Standard systems are fabricated in stainless steel and all used components are fully documented and tested. Systems are available in explosion proof versions that fulfil the requirements for Europe (ATEX) or US (Class One Div xx). Systems for Europe are CE marked and designed according to ASME BPE

The systems are mobile and can be moved around within the facility. Easy installation and connection for quick start-up.