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Ionic™ Purification System from Purigen

Purigen Biosystems, Inc., a leading provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, today announced the launch of its Ionic™ Purification System.

The small benchtop system utilizes the company’s core isotachophoresis (ITP) technology to extract, purify, and concentrate nucleic acids from biological samples in one hour with less than three minutes of hands-on time per sample. Purigen will unveil the new system and present data during the Association for Molecular Pathology (AMP) 2019 Annual Meeting and Expo.

The Ionic Purification System enables the automated extraction of nucleic acids with dramatically increased yields and improved purity from a wide range of sample types, including cultured or sorted cells and formalin-fixed, paraffin-embedded (FFPE) tissues. Biological samples are gently lysed and then loaded into the Ionic™ Fluidics Chip. The Ionic system then applies an electric field to the chip and the nucleic acids are isolated in their natural, native form using the company’s proprietary ITP technology. The nucleic acids are not denatured or dehydrated, and there is no binding or stripping from fixed surfaces. The process minimizes fragmentation and eliminates any bead or buffer contamination. The extracted nucleic acids are pure, abundant, and ready for analysis by any downstream technique such as next-generation sequencing or PCR.

Ionic Purification System Components

  • The Ionic™ Purification Instrument – A small benchtop system driven by a simple touchscreen interface that can process one fluidics chip with eight samples in approximately one hour
  • Ionic™ FFPE to Pure DNA Kit – Consists of six chips and a reagent set with all necessary enzymes and buffers to perform DNA extraction directly from as many as 48 FFPE scrolls or slides
  • Ionic™ Cells to Pure DNA Kit – Consists of six chips and a reagent set with all necessary enzymes and buffers to perform cell lysis and DNA extraction from cultured or sorted cells in up to 48 samples

“The new Ionic Purification System will fundamentally change how nucleic acids are purified from precious samples prior to downstream analysis using NGS and PCR,” said Barney Saunders, PhD, CEO of Purigen. “When working with challenging sample types such as FFPE, or with small tissue samples, the ability to purify nucleic acids with maximal yield and quality is crucial. More abundant and higher-quality nucleic acids allow for superior quality data, which provides researchers with improved biological insights and empowers clinicians with more actionable information.”

The Ionic Purification System is available now through Purigen’s direct sales channels. For more information, please visit: https://www.purigenbio.com/products/ionic-system.

Company Name: Purigen Biosystems, Inc.
About Company: Purigen Biosystems is redefining nucleic acid sample preparation with an innovative platform based on the highly efficient isotachophoresis technology invented by Juan Santiago, PhD, and his team at Stanford University. Purigen’s automated benchtop instrumentation and accompanying microfluidic chip purify nucleic acid samples from a wide variety of sources, including minute or otherwise challenging cancer samples. The purified nucleic acids are then immediately compatible with a wide range of downstream detection methods, including next-generation sequencing, PCR, and other genomic tests.
Person of Contact: Nicole Litchfield
Phone: 415-793-6468

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