East River BioSolutions announced the release of NativeCoat™ ECM – a novel line of 2D in vitro cell culture coatings comprised of native tissue-derived extracellular matrix (ECM) that enables scientists to study cells in their tissue-specific microenvironments, leading to more physiologically relevant testing and thus more accurate and actionable scientific results.
Despite numerous advances in cell culture, faithfully replicating human physiology in vitro remains a significant challenge. Current substrates fail to provide the key factors necessary for cells in vitro to maintain their normal identity and activity and thrive as they would in the body. Current top-selling products are comprised of a single biochemical component or derived from rodent tumor sources. These are either too simple to provide the biochemical factors that make up the native cellular environment and support limited cell function, or they artificially alter cell growth and function, neither of which is conducive to attaining accurate data for successful scientific outcomes.
In contrast, East River Bio's NativeCoat™ ECM coatings provide the complete milieu of the microenvironment – the ECM specific to each tissue and cell type. NativeCoat™ ECM can be used to coat any cell culture surface, bringing the highly specific composition of the native cell environment to any in vitro setting and thus allowing scientists to improve cell attachment and viability and enhance physiologic function. NativeCoat™ ECM substrates are available for multiple cell types, including liver, lung, heart and others.
Dr. Gordana Vunjak-Novakovic, University Professor at Columbia University and Founder and Chair of the Board of East River Bio, stated: "Scientists' ability to recreate the native microenvironment in which they study cells is key to successful biological research and drug development. Because they are derived from native tissue sources, NativeCoat™ ECM substrates provide the most physiologically relevant microenvironments possible for those seeking to study how cells behave under controllable conditions in vitro. This is an important part of the paradigm shift toward tools that allow scientists to conduct physiologically relevant research and better science overall."
For more details, view: http://www.eastriverbio.com